Researchers Propose 10 Biological Hallmarks to Explain Facial Aging
A proposed framework links facial aging to 10 tissue processes, but studies must show whether it improves treatment decisions.
Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
338 articles
A proposed framework links facial aging to 10 tissue processes, but studies must show whether it improves treatment decisions.
A stiffer growth surface helped aging stem cells regain shape and multiply in the lab, suggesting a possible tool for regenerative medicine.
Japanese researchers will transplant patients' own chemically reprogrammed liver progenitor cells into the portal vein in a first-in-human cirrhosis safety trial.
A review explores how mitochondrial transplants might repair damaged tissues—and why dosing, safety, and manufacturing remain major hurdles.
Four weeks of cyclic Yamanaka factor expression reduced ischemic brain damage and preserved neurons and myelin in aged mice assessed 48 hours after stroke.
Lipid nanoparticle-delivered circular RNA encoding OCT4, SOX2 and KLF4 rejuvenated senescent stem cells in vitro without triggering pluripotency.
Could resetting cellular aging reshape plastic surgery? A new perspective explores the possibilities, but offers no patient outcome data.
A procedural review reports improvements in facial skin quality with processed fat, but leaves the size and durability of benefits unclear.
A completed 10-patient trial tested a stem cell product for chronic spinal cord injury, but the supplied abstract reports no safety or recovery results.
A new review reveals stem cell senescence as the shared root cause of osteoporosis, osteoarthritis, and disc degeneration — and maps emerging therapies.
Bone marrow stem cell exosomes deliver XPO7, which suppresses KDM2B to reverse chondrocyte senescence and halt osteoarthritis progression in rats.
Human iPSC-derived tissue-engineered nigrostriatal pathways restore dopamine release in rats for up to 6 months, offering a new path for Parkinson's repair.