Diet science, macronutrients, fasting, and nutritional interventions for longevity
439 articles
In 13,528 U.S. adults, higher methyl-donor nutrient scores tracked with lower frailty odds. Oxidative stress may help explain the association.
Cutting calories altered immune-related genes in aged rats' fat, but metabolic markers stayed unchanged. Exercise tempered the gene response.
A small trial links daily peanuts to better insulin responses in memory-related brain regions, but dementia prevention remains unproven.
A large U.S. analysis finds no protective effect of alcohol at any level, with risks of cancer, heart disease and early death rising from low intake.
A systematic review of 10 RCTs (1,098 adults) compares low-carb, low-GI, Mediterranean and fasting diets for prediabetes. Each helps, but none is best for everyone.
A sports nutrition review weighs the evidence on calorie surpluses, weight loss without restriction, intermittent fasting and sex differences in fasting.
A review finds modest weight and waist benefits from fasting, but mixed metabolic results and uncertainty about benefits beyond calorie reduction.
Broccoli sprouts cleared H. pylori in 56% of patients in trials, while diet shaped stomach cancer risk even in genetically vulnerable people.
A nutrition review outlines protein targets, resistance training, and nutrient monitoring to support healthier weight loss with GLP-1 drugs.
A study of nearly 90,000 adults ties dietary Neu5Gc, a sugar in beef and lamb, to a 63% higher type 2 diabetes risk, possibly through chronic inflammation.
A 120-person trial is testing calorie restriction for inherited polycystic kidney disease. This protocol reports baseline data, not treatment benefits.
Cambridge researchers tested 39 sweeteners on 25 gut bacteria species. Three-quarters altered growth, and isosteviol plus duloxetine had striking effects in the lab.
