Topic

Strength & Fitness

Exercise science, resistance training, VO2max, and physical performance

396 articles

Jeff Cavaliere on Smarter Resistance Training to Build Muscle and Protect Joints After 40
Exercise & Fitness

Jeff Cavaliere on Smarter Resistance Training to Build Muscle and Protect Joints After 40

Physical therapist Jeff Cavaliere explains how to adjust training intensity, volume, and exercise choice in midlife to keep building muscle while lowering injury risk.

Podcast
Nov 4, 2026 0
Bestform Trial Tests Twice-Weekly Exercise to Preserve Mobility in Older Adults
Exercise & Fitness

Bestform Trial Tests Twice-Weekly Exercise to Preserve Mobility in Older Adults

A 404-participant trial tests strength, coordination, and endurance training in retirement homes. The supplied abstract does not report results.

Clinical Trial
Nov 3, 2026 0
Build Strength as You Age Without Letting Training Wear You Down
Exercise & Fitness

Build Strength as You Age Without Letting Training Wear You Down

Peter Attia and Jeff Cavaliere discuss balancing hard training, recovery, and exercise selection to keep building strength as you age.

Video
Nov 3, 2026 0
Fitter Youth With Multiple Sclerosis Show Larger Brain Volumes and Fewer Lesions
Exercise & Fitness

Fitter Youth With Multiple Sclerosis Show Larger Brain Volumes and Fewer Lesions

In 33 young patients with MS, higher fitness tracked with larger brain volumes and lower lesion volume. The study cannot establish cause and effect.

Research Paper
Nov 2, 2026 0
The Oxygen Cascade Under Load: Stroke Volume, Mitochondria, and the Mortality Signal in VO2 Max
Exercise & Fitness
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The Oxygen Cascade Under Load: Stroke Volume, Mitochondria, and the Mortality Signal in VO2 Max

A mechanistic look at what sets VO2 max: cardiac filling, hemoglobin mass, muscle diffusion, and the PGC-1α signaling that rebuilds muscle. Includes how well the mortality evidence holds up.

TutorialAdvanced
Oct 31, 2026 0
Inside the Oxygen Pipeline: What Actually Limits Your VO2 Max
Exercise & Fitness
Premium

Inside the Oxygen Pipeline: What Actually Limits Your VO2 Max

Break VO2 max into its working parts: cardiac output, blood volume, and muscle extraction. See which part limits you, how training reshapes each one, and why the number alone doesn't predict race pace.

TutorialIntermediate
Oct 30, 2026 0
Effort-Based Pacing Matches Speed-Based Interval Training for Aerobic Gains With Less Strain
Exercise & Fitness

Effort-Based Pacing Matches Speed-Based Interval Training for Aerobic Gains With Less Strain

Running intervals by perceived effort gave the same time near VO2max as speed-based pacing, with lower heart rate, lactate and perceived exertion.

Research Paper
Oct 30, 2026 0
Four Weeks of Aerobic Training Reshapes Gut Bacteria in Middle-Aged Mice
Exercise & Fitness

Four Weeks of Aerobic Training Reshapes Gut Bacteria in Middle-Aged Mice

Aerobic training changed gut microbial composition in middle-aged male mice, but whether those changes drive fitness benefits remains unclear.

Research Paper
Oct 30, 2026 0
VO2 Max for Beginners: How Your Body Turns Air Into Energy
Exercise & Fitness
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VO2 Max for Beginners: How Your Body Turns Air Into Energy

VO2 max is a measure of how much oxygen your body can use during hard effort, and it is one of the strongest fitness predictors of long-term health. Learn what it means, how to estimate yours, and how to raise it.

TutorialBeginner
Oct 29, 2026 0
Marathon Running Disrupts Some Recovery Measures More Than Trail Running
Exercise & Fitness

Marathon Running Disrupts Some Recovery Measures More Than Trail Running

In 41 trained runners, a simulated marathon caused greater thigh activation losses and slower recovery than trail runs matched for effort.

Research Paper
Oct 26, 2026 0
The Eroding Safety Factor: Molecular Mechanisms of Neuromuscular Failure in Sarcopenia
Exercise & Fitness
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The Eroding Safety Factor: Molecular Mechanisms of Neuromuscular Failure in Sarcopenia

A mechanism-level look at how the nerve-muscle synapse loses transmission reliability, why denervated fibers trigger a transcriptional program that sprouting can't always answer, and what human data support or limit these ideas.

TutorialAdvanced
Oct 25, 2026 0
Fitness predicts survival in kidney disease regardless of body weight
Exercise & Fitness

Fitness predicts survival in kidney disease regardless of body weight

In 13,521 veterans with kidney disease, the fittest had about half the mortality risk of the least fit, whatever their BMI. Higher BMI also tracked with lower mortality.

Research Paper
Oct 25, 2026 0
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