Get Longevity Research Delivered Weekly
Join thousands of health professionals and curious minds. No spam, ever.
Enter your email to subscribe:
Your AI Longevity Team
Categories
TrendingLatest Summaries
Fresh from academic journals, YouTube, podcasts, and other sources
Blood antibody patterns flag inflammatory bowel disease a decade before diagnosis
A study of 2,000 blood samples found narrowed antibody diversity and distinct immune signatures up to 10 years before Crohn's or ulcerative colitis diagnosis.
Osteoporosis Drugs Tied to Up to 24% Lower Dementia Risk in 120,000 Older Adults
A Hong Kong study of 120,000+ adults over 60 links common bone-strengthening bisphosphonates to a lower risk of Alzheimer's and other dementias.
Gut Microbes Trigger Liver Signals That Limit Cancer and Gene Therapy Delivery
Blocking gut-driven serotonin signals improved delivery of cancer and gene therapies, but clinical benefits and safety remain unproven.
Gut bacteria may decide whether pancreatic cancer responds to immunotherapy
A review of how gut microbes and their metabolites shape the pancreatic tumor immune environment and could improve immunotherapy response.
New Framework Challenges Claims That Cosmetic Treatments Regenerate Skin
Smoother skin does not necessarily mean regenerated skin. A new framework separates cosmetic improvement from restoration of skin biology.
SGLT2 Inhibitors Show Lower Self-Harm Risk in Type 2 Diabetes Study
Two observational comparisons link SGLT2 diabetes drugs to lower self-harm risk, but they do not establish a protective effect.
Heart Calcium Scans Narrow Statin Recommendations but Leave Prevention Questions Open
A major trial found fewer statin recommendations and better adherence with heart scans, but did not establish equivalent cardiovascular protection.
Full-Fat Dairy Leaves Weight and Cholesterol Unchanged in a Small 12-Week Trial
A trial in 74 adults challenges assumptions about full-fat dairy, but its short duration and differing calorie targets limit the conclusions.
GLP-1 Drugs Reduce Cardiovascular Risk, but New Analysis Cannot Rank Them Reliably
Ten trials support GLP-1 drugs' cardiovascular benefits, but a new model cannot reliably show which works best or how protection changes over time.
Higher Methyl-Donor Nutrient Intake Tracks With Lower Frailty Odds
In 13,528 U.S. adults, higher methyl-donor nutrient scores tracked with lower frailty odds. Oxidative stress may help explain the association.
UK Lupus Study Finds Unequal Responses After Treatment Escalation
Only 23% met major response criteria after stronger lupus treatment. Black patients had greater initial disease burden and lower observed response.
Povorcitinib Improves Facial Pigmentation in Two Phase 3 Vitiligo Trials
A daily pill improved facial pigmentation in two yearlong vitiligo trials, but only about one in five patients reached the main treatment target.
NAD+ Supplements Alone Fall Short Against Age-Related Muscle Loss
A review finds NAD+ precursors have not improved muscle mass or strength in older adults, while exercise combinations remain unproven.
Injectable Gel Helps a Repair Protein Rebuild Injured Muscle in Preclinical Study
A gel released Cripto for up to 28 days and improved muscle repair in a preclinical model, while a single protein injection did not.
Statins May Help Build Bone After Menopause Through a Stem Cell Pathway
Statin use tracked with slower bone loss after menopause, while experiments revealed how atorvastatin may support bone formation when estrogen is low.
Sleep Breathing Problems May Mask Leg Movements Linked to Poorer Rest
A study of 481,857 adults links nighttime limb movements to poorer sleep and health conditions—and suggests breathing problems may obscure them.
Our Sponsors

Bioscope.AI
AI-Powered Precision Longevity for Physicians on the Leading Edge

Therabot
Therabot: Real Massage. Real Recovery.

Bioscope Foundry
We make it easy to launch your own precision longevity concierge practice

100 Is the New 30
How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime — Jeffrey Gladden, MD, FACC

MySuperFriends
A private world of AI companions — coaches, therapists, teachers, and guides who remember you and grow with you over time.















