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Fresh from academic journals, YouTube, podcasts, and other sources
Researchers Explore Existing Medicines as Kidney Cancer Treatments
A review explores familiar drugs as kidney cancer treatments, but the abstract provides no clinical benefit estimates.
Thick Fluid Around Glioblastoma Makes Brain Cancer Cells Smaller and More Invasive
Chinese researchers found that the viscous fluid at a glioblastoma's edge reshapes tumor cells, making them more flexible, more invasive, and changed even after they leave it.
Disabling MTCH2 Boosts Fat Burning in Human Cells and Endurance in Mice
A protein called MTCH2 may influence fat burning and muscle endurance, but the evidence remains limited to cells and mice.
Rituximab for multiple sclerosis linked to a tenfold higher risk of inflammatory bowel disease
A Swedish study of 13,748 MS therapy episodes finds rituximab users developed IBD far more often than users of other modern MS drugs, mostly Crohn disease.
Fitness predicts survival in kidney disease regardless of body weight
In 13,521 veterans with kidney disease, the fittest had about half the mortality risk of the least fit, whatever their BMI. Higher BMI also tracked with lower mortality.
Sirolimus and paclitaxel drug-coated balloons perform similarly in coronary arteries
A meta-analysis of 8 trials and 1,043 patients finds sirolimus- and paclitaxel-coated balloons deliver similar results in coronary artery disease, with a few caveats.
Intermittent Fasting Shows Modest Metabolic Benefits but Leaves Key Questions Unanswered
A review finds modest weight and waist benefits from fasting, but mixed metabolic results and uncertainty about benefits beyond calorie reduction.
Major Obesity Trials May Miss the Full Burden of GLP-1 Nausea
A review finds major obesity trials tracked nausea without dedicated patient questionnaires, potentially missing its everyday burden.
Gut Bacteria Use Bile Chemistry to Displace Antibiotic-Resistant Enterococci
A bacterial partnership changes bile chemistry to suppress resistant gut microbes, pointing toward new infection-prevention strategies.
Glucagon Boosts Calorie Burning in Obese Mice Through Liver Signaling
A mouse study links glucagon's obesity-specific calorie-burning effect to liver signaling, offering clues for future weight-loss drugs.
Nicotinamide Riboside Improves Skin Flap Survival in Rats
NR protected skin flaps in rats and boosted cellular recycling, pointing to a possible tissue repair application—not proven benefits in humans.
Scientists Map 13,403 KCNQ1 Variants to Clarify Inherited Heart Rhythm Risk
A large laboratory map links KCNQ1 gene changes to abnormal heart rhythms and could help clarify uncertain genetic test results.
Gut-Derived Butyrate Shows Promise for Brain Aging, but Human Evidence Lags
Gut bacteria turn fiber into butyrate, which may influence brain aging. A new review explores the mechanisms—and the gaps in human evidence.
Review Questions Device Safety for Facial Volume Loss After GLP-1 Treatment
Facial tightening devices may affect already depleted fat after GLP-1 weight loss, but direct safety evidence remains limited.
Sleep Breathing Problems May Mask Leg Movements Linked to Poorer Rest
A study of 481,857 adults links nighttime limb movements to poorer sleep and health conditions—and suggests breathing problems may obscure them.
Plant Sterols Fail to Lower LDL in a Small Trial of Adults With Obesity
A small randomized trial found 2 grams of plant sterols daily did not improve LDL cholesterol or other metabolic measures versus placebo.
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