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Fresh from academic journals, YouTube, podcasts, and other sources
Mayo Clinic maps zombie cells and finds new ways to quiet them
Seven Mayo Clinic studies reveal why senescent cells fuel inflammation and test new ways to target them, including a tomato compound that helped aging mice.
Excess RNA Can Damage Mitochondria and Disrupt Cellular Energy
A study links excess RNA to mitochondrial damage, revealing a potential connection between cellular cleanup, infections, and aging-related disease.
Epigenetic Reprogramming Gene Therapy Shows Early Vision Gains in First Human Glaucoma Trial
Life Bio's ER-100, which delivers OSK reprogramming factors to the eye, was well tolerated in three glaucoma patients, and two showed visual field gains.
Two Vitamin E Forms Show Different Links to Cancer and Alzheimer's Mortality
Higher blood levels of two vitamin E forms tracked with lower mortality in older adults, but the findings do not establish supplement benefits.
Aging biology may explain why systemic sclerosis looks so different from patient to patient
A new review proposes that biological aging, not just birthdays, may help shape who gets systemic sclerosis, which organs are affected, and why comorbidities pile up.
Rapamycin Helps Injured Nerves Recover and Preserves Muscle in Mice
In mice, rapamycin improved nerve repair, preserved muscle, and supported walking recovery after injury. Human benefits remain unproven.
Marathon Running Disrupts Some Recovery Measures More Than Trail Running
In 41 trained runners, a simulated marathon caused greater thigh activation losses and slower recovery than trail runs matched for effort.
Disabling MTCH2 Boosts Fat Burning in Human Cells and Endurance in Mice
A protein called MTCH2 may influence fat burning and muscle endurance, but the evidence remains limited to cells and mice.
Rituximab for multiple sclerosis linked to a tenfold higher risk of inflammatory bowel disease
A Swedish study of 13,748 MS therapy episodes finds rituximab users developed IBD far more often than users of other modern MS drugs, mostly Crohn disease.
Sirolimus and paclitaxel drug-coated balloons perform similarly in coronary arteries
A meta-analysis of 8 trials and 1,043 patients finds sirolimus- and paclitaxel-coated balloons deliver similar results in coronary artery disease, with a few caveats.
Gut Bacteria Use Bile Chemistry to Displace Antibiotic-Resistant Enterococci
A bacterial partnership changes bile chemistry to suppress resistant gut microbes, pointing toward new infection-prevention strategies.
Nicotinamide Riboside Improves Skin Flap Survival in Rats
NR protected skin flaps in rats and boosted cellular recycling, pointing to a possible tissue repair application—not proven benefits in humans.
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