Pelacarsen slashes Lp(a) by 78% yet fails to cut heart attacks and strokes
The Lp(a) HORIZON trial found pelacarsen dramatically lowered lipoprotein(a) but did not reduce cardiovascular events, leaving hopes on next-gen siRNA drugs.
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The Lp(a) HORIZON trial found pelacarsen dramatically lowered lipoprotein(a) but did not reduce cardiovascular events, leaving hopes on next-gen siRNA drugs.
A major trial found fewer statin recommendations and better adherence with heart scans, but did not establish equivalent cardiovascular protection.
A trial in 74 adults challenges assumptions about full-fat dairy, but its short duration and differing calorie targets limit the conclusions.
Novartis reports nine tumors after Zolgensma treatment, including two cases with vector DNA integration. Cancer risk remains uncertain.
A six-month trial found better artery function with NOVOS Core, but participant losses, age differences, and industry funding warrant caution.
A study of more than 41,000 dogs links canine and human mortality patterns, offering clues—not proof—about shared influences on longevity.
A UK study links an extra year of compulsory schooling to fewer dementia diagnoses, with the strongest benefit among adults with genetic risk.
A zebrafish study links an immune-cell recruiting signal to tissue protection, opening research paths for inflammatory diseases and cancer.
UC Berkeley researchers link tau buildup in the frontal cortex to disrupted slow waves in deep sleep and weaker overnight memory consolidation.
Japanese scientists found a compound that shields muscle-repair protein HGF from age-related damage and more than doubles its receptor binding in early mouse studies.
A UCLA study links pesticide exposure to higher Parkinson’s risk, while lab experiments suggest how the chemical may damage brain cells.
A mouse study suggests fear makes safe and threatening memories overlap, offering a possible clue to anxiety and PTSD—but not a treatment yet.