8332 articoli in questo argomento
In mice with chemically induced liver scarring, the NAMPT inhibitor FK866 lowered liver injury, fibrosis markers, and inflammation, pointing to a new target.
HyperProbe1.1 images glioma tissue in about 30 seconds, mapping hemoglobin, cytochromes, and NADH/FAD without contrast agents, a step toward real-time neuronavigation.
A fully oral blend of pterostilbene, silybin, nicotinamide riboside and captopril helped 90% of mice survive lethal X-rays while sparing tumor radiotherapy effects.
A 2026 review says high-dose taurine prevented stroke-like episodes in 60% of MELAS patients, while sonlicromanol and gene editing advance.
A narrative review explores how age-related CHIP mutations in blood stem cells, and possibly in vessel walls, drive inflammation and cardiovascular risk.
A new review explains why TET2 loss fuels age-related blood clones and inflammation yet can strengthen engineered CAR-T cells, depending on cell type and context.
A JCI commentary explains how DNMT3A drives DNA repair in macrophages after efferocytosis and why clonal hematopoiesis mutations may impair plaque healing.
Boosting the antioxidant enzyme GPX4 in retinal ganglion cells promoted optic nerve regrowth, cell survival, and vision in mouse optic nerve injury and glaucoma models.
A review lays out how to define and track bacterial strains in FMT and live biotherapeutics, from culturing to metagenomics, to link engraftment with clinical outcomes.
A systematic review of 33 studies (2,112 patients) finds gut-microbiome therapies safe and linked to acne lesion reductions, though not clearly better than controls.
A head-to-head test shows virus-free mRNA-LNP reprogramming matches Sendai virus iPSCs and cardiomyocytes while reaching milestones in fewer passages.
L'IA generativa ha progettato un nuovo inibitore di PKMYT1 e lo ha trasformato in un degradatore orale che ha ridotto i tumori nei modelli xenograft murini.
