Longevity Pulse — Science-Backed Insights for a Longer, Healthier Life

Brain Health

Study Links Gut Bacteria and Brain Fluid Clearance to Alzheimer's Disease

A study of 164 adults links specific gut bacteria, neurotransmitter metabolites, and brain fluid clearance markers with cognitive impairment.

Heart Health

Routine Clinical Measurements Help Estimate Fitness in Heart Failure

In 5,176 heart failure patients, clinical measurements helped estimate peak oxygen uptake and identify groups with different survival outcomes.

Gut & Microbiome

Nanoformulated Curcumin Protects the Gut in Mice by Reshaping Its Microbes

Giving mice nanoformulated curcumin before colitis reduced inflammation and gut barrier damage. Microbe transfers helped establish how it worked.

Cancer Research

Immune Aging May Matter More Than Birthdays for Cancer Immunotherapy

A review explores how immune aging shapes cancer treatment response—and why rejuvenation strategies still need clinical validation.

Oct 13, 2026 0

Nutrition & Diet

Olive Oil Before Carbs Reduced Blood Sugar Spikes in Mice

Mouse research suggests eating olive oil before carbohydrates can blunt blood sugar spikes. Human benefits and optimal doses remain unproven.

Press Release

Oct 12, 2026 0

Nutrition & Diet

Restricting Methionine and Calories Reshapes Liver Antioxidant Chemistry Differently in Rats

Two longevity-focused diets changed liver chemistry differently in male rats, challenging the idea that all dietary restriction works alike.

Oct 12, 2026 0

Sleep & Recovery

Weight Loss Can Improve Sleep Apnea but May Not Replace Breathing Therapy

A new review explains how weight loss, tirzepatide, and breathing devices can work together to treat obesity-related sleep apnea.

Oct 11, 2026 0

Supplements

NAC May Protect Stressed Pancreatic Cells but Disrupt Healthy Insulin Signaling

A review suggests NAC can protect stressed insulin-producing cells, but excessive antioxidant exposure may interfere with their normal function.

Oct 11, 2026 0

Hormones

Immune Changes May Drive Ovarian Aging and Reveal New Treatment Targets

A review links ovarian aging to inflammation and immune dysfunction, highlighting experimental treatments—not proven ways to extend fertility.

Oct 10, 2026 0

Exercise & Fitness

Diabetes Adds a Fitness Burden in Chronic Kidney Disease

Adults with kidney disease and diabetes had lower aerobic fitness, but resting heart rate variability did not explain the difference.

Oct 10, 2026 0

Supplements

NMN and NR Raise NAD+ but Have Not Proven They Slow Aging

NMN and NR can raise blood NAD+, but longer, healthier lives remain unproven. Independent testing matters more than anti-aging promises.

Oct 10, 2026 0

Exercise & Fitness

Your Fitness Level Predicts Death Risk Better Than Cholesterol or Blood Pressure Alone

A 562,000-person study shows cardiorespiratory fitness meaningfully reclassifies 10-year mortality risk beyond standard risk factors.

Autoimmune & Arthritis

Senolytics and Senomorphics May Offer a New Treatment Angle for Giant Cell Arteritis

Cellular senescence drives vascular inflammation in giant cell arteritis. Could senolytics like fisetin and quercetin reshape treatment?

Sleep & Recovery

Digital CBT for Insomnia Delivers Clinically Meaningful Sleep Gains Across 14,000 People

A 20-year meta-analysis of the SHUTi program finds internet-delivered CBT-I cuts insomnia severity by 8+ points and slashes wake time by 35+ minutes.

Regenerative Medicine

Nanoparticles Sharpen the Attack on Senescent Cells Driving Aging

A new review maps how engineered nanoparticles can precisely deliver senolytic and senomorphic agents to clear or quiet aging cells.

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100 Is the New 30

How Playing the Symphony of Longevity Will Enable Us to Live Young for a Lifetime — Jeffrey Gladden, MD, FACC

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Tutorials

Heart HealthIntermediate

Retrograde Brakes and Fading Tone: How Endocannabinoid Signaling Changes With Age

Longevity & AgingBeginner

Oct 9, 2026

Your Body's Hidden Calm System: The Endocannabinoid System Explained

Longevity & AgingAdvanced

Oct 8, 2026

AhR as a Longevity Target: Crosstalk, Epigenetics, and Therapeutic Frontiers

Longevity & AgingIntermediate

Oct 7, 2026

AhR Signaling Pathways: From Ligand Binding to Longevity Outcomes

Longevity & AgingBeginner

Oct 6, 2026

Your Cells Have a Pollution Sensor — And It Affects How You Age

Oct 5, 2026

Metabolic HealthAdvanced

Ceramide Signaling at the Molecular Frontier: Lipotoxic Mechanisms in Aging Biology

Metabolic HealthIntermediate

Oct 4, 2026

Ceramide Signaling: How Toxic Lipids Hijack Your Cell's Control Systems

Oct 3, 2026

Metabolic HealthBeginner

When Fat Turns Toxic: Understanding Ceramides and Your Aging Cells

Longevity & AgingAdvanced

Oct 2, 2026

Xenobiotic Metabolism at the Systems Level: Epigenomics, Interindividual Variation, and Therapeutic Targeting