Stem cell therapies, regenerative medicine, tissue engineering, and cellular reprogramming
338 articles
Scientists have joined the circulatory systems of young and old animals to see what blood carries. Here's what they found, what got overhyped, and what it means for you.
A patient-derived stem cell line carrying a rare DSG2 mutation opens new doors for studying and treating a deadly inherited heart disease.
A systematic review of 20 studies finds autologous blood-derived biofillers deliver favorable outcomes and a strong safety profile for facial regeneration.
Aging skin loses its ability to heal wounds — new review outlines how secretome-based biologics and smart delivery systems could restore that capacity.
Aspen Neuroscience's autologous iPSC-derived dopaminergic neuron therapy clears genomic quality control and shows efficacy in rodent models of Parkinson's.
A new molecular pathway reveals why steroid-treated muscles struggle to regenerate — and points to a druggable target.
A zebrafish and human iPSC study reveals how Bnip3lb-driven mitophagy regulates ROS to preserve hematopoietic stem cell multipotency and expand transplantable progenitors.
Alternative splicing rewires DNA repair genes in aging stem cells independently of transcription, revealing a new layer of cellular aging control.
A sweeping review maps bone aging across molecular, cellular, and systemic levels — and charts emerging therapies to reverse it.
Tissue-resident Tregs co-opt inflammatory cytokines IFNγ and IL-10 to drive intestinal stem cell regeneration after radiation or transplant injury.
Researchers detail a reproducible multiplex method to profile SASP factors in primary and iPSC-derived skin fibroblasts, advancing senescence research.
A comprehensive review maps bone aging from DNA to whole skeleton and surveys every intervention from exercise to senolytics.
