9 722 articles
A new study identifies Traf6 as a master regulator of inflammatory senescence in bone marrow stem cells, opening a targeted path to treat age-related osteoporosis.
A newly discovered molecular switch pushes aging bone marrow stem cells to make fat instead of bone, accelerating osteoporosis.
A new review reveals how Chinese herbal medicine induces cancer cell senescence via telomere shortening, DNA damage, and SASP regulation.
Scientists identify a novel disease-associated radial glia-like cell population in progressive MS brains with epigenetically dysregulated interferon signaling.
Losing progranulin accelerates vascular senescence, inflammation, and fibrosis—even in young adult mice—linking this protein to early cardiovascular aging.
A mouse study finds that blocking activin receptors strengthens trabecular bone, though high-fat diet obesity blunts the effect.
A comprehensive review reveals how endocrine dysfunction fuels the dangerous combination of muscle loss and fat gain, with implications for treatment.
Exosomes harvested from hyper-muscular mice counteract dexamethasone-induced atrophy, pointing to a novel cell-free therapy for sarcopenia.
Fibroblast-derived exosomes change with age, altering how keratinocytes differentiate — revealing a key mechanism in skin aging.
Scientists packaged the full telomerase enzyme into extracellular vesicles and reversed multiple hallmarks of aging in aged mice.
L'irisine active la voie AMPK-Beclin1 pour restaurer l'autophagie bloquée et réduire l'inflammation dans des modèles d'exposition à la fumée de cigarette et d'infection bactérienne.
Des scientifiques découvrent comment GPR107 stabilise BECN1 pour alimenter l'autophagie sécrétoire, la prolifération des kératinocytes et l'inflammation cutanée chronique dans le psoriasis.
