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Your Gut Bacteria May Predict How Fast You Are Biologically AgingGut & Microbiome

Your Gut Bacteria May Predict How Fast You Are Biologically Aging

Researchers at the University of Hawaii developed machine learning models linking gut bacteria composition to biological aging speed, measured by DNA methylation. Using data from 123 participants including Native Hawaiians and Pacific Islanders, they found that certain gut microbes were significantly associated with DunedinPACE — a cutting-edge biomarker estimating how fast someone is aging biologically. Notably, Bifidobacterium adolescentis was the strongest predictor of slower aging, while Succinivibrio dextrinosolvens was linked to faster aging. These associations were independent of a person's chronological age, suggesting the gut microbiome may directly influence the pace of aging itself. The findings are hypothesis-generating and not yet ready for clinical diagnostics, but point to the gut-epigenome axis as a promising target for longevity interventions.

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