Gut & MicrobiomeMulberry Compounds Reshape Gut Bacteria and Boost Metabolic Health
A review from Wroclaw Medical University finds that compounds in mulberry leaves and fruit — including polyphenols, polysaccharides, and 1-deoxynojirimycin — may reshape the gut microbiome in ways that benefit metabolic health. Studies in animals show shifts toward beneficial bacteria, higher production of short-chain fatty acids like butyrate and propionate, and improvements in glucose and lipid markers. The effects vary significantly depending on whether leaves or fruit are used, the mulberry species, and how the plant material is processed. Combining multiple mulberry compounds appeared to produce stronger results than single extracts in mouse studies. Researchers caution that human trials are still needed before any firm conclusions can be drawn about real-world benefits.
