Regenerative MedicineMitochondrial Transplants Could Reshape Metabolism and Immune Activity
Transplanting healthy mitochondria, the tiny energy producers inside cells, could potentially help damaged tissues recover. This review explores how the approach might also change fuel use, cellular cleanup, and immune activity rather than simply replace lost energy. The authors discuss experimental and clinical applications across several organs, plus cancer and aging research. They also examine how mitochondria are collected, preserved, and delivered. However, major barriers remain: manufacturing methods vary, effective doses are unclear, and immune reactions and long-term safety need further study. The abstract provides no numerical treatment benefits or evidence that transplantation extends human healthspan. For now, this is an experimental treatment strategy, not an established anti-aging intervention. This summary is based only on the abstract, which limits assessment of the underlying evidence.