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Microplastics Infiltrate the Developing Brain and Trigger Lasting Neurological DamageBrain Health

Microplastics Infiltrate the Developing Brain and Trigger Lasting Neurological Damage

Micro- and nanoplastics (MNPs) are everywhere — in food, water, and air — and new research confirms they can cross both the placental and blood-brain barriers. This systematic review analyzed 20 rodent studies examining MNP exposure during gestation, lactation, and early life. Consistent findings emerged across all developmental windows: oxidative stress, mitochondrial dysfunction, neuroinflammation, disrupted neurogenesis and myelination, and abnormal synaptic connectivity. Behavioral consequences included impaired learning and memory, increased anxiety, reduced sociability, and repetitive behaviors — patterns resembling neurodevelopmental disorders. Gut microbiome disruption appeared to amplify brain effects via the gut-brain axis. While direct human evidence is lacking, these findings raise serious concerns about ubiquitous plastic exposure and its potential to shape long-term brain health and cognitive function.

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