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Mechanotransduction at the Molecular Level: Integrin Conformational Dynamics, Force Transmission, and Therapeutic Targeting in Aging Tissue

A quantitative look at how integrin tension becomes YAP/TAZ and TGF-β signaling, why aged tissues fail in opposite directions, and what integrin-directed trials have actually delivered.

Thursday, July 30, 2026 3 views
Tutorial: Mechanotransduction at the Molecular Level: Integrin Conformational Dynamics, Force Transmission, and Therapeutic Targeting in Aging Tissue

About This Tutorial

A quantitative look at how integrin tension becomes YAP/TAZ and TGF-β signaling, why aged tissues fail in opposite directions, and what integrin-directed trials have actually delivered.

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