Biological age reversal, epigenetic clocks, senolytics, and anti-aging interventions
2.814 artigos
A new study identifies Traf6 as a master regulator of inflammatory senescence in bone marrow stem cells, opening a targeted path to treat age-related osteoporosis.
A newly discovered molecular switch pushes aging bone marrow stem cells to make fat instead of bone, accelerating osteoporosis.
A new review reveals how Chinese herbal medicine induces cancer cell senescence via telomere shortening, DNA damage, and SASP regulation.
Scientists identify a novel disease-associated radial glia-like cell population in progressive MS brains with epigenetically dysregulated interferon signaling.
Losing progranulin accelerates vascular senescence, inflammation, and fibrosis—even in young adult mice—linking this protein to early cardiovascular aging.
Fibroblast-derived exosomes change with age, altering how keratinocytes differentiate — revealing a key mechanism in skin aging.
Scientists packaged the full telomerase enzyme into extracellular vesicles and reversed multiple hallmarks of aging in aged mice.
Go beyond the basics and explore the molecular machinery that keeps your nuclear envelope intact — and the precise failure modes that drive cellular aging when it breaks down.
A topical senolytic drug cleared senescent cells from aging skin and boosted wound closure rates by 43% in older mice, hinting at new treatments for slow-healing wounds.
A mouse study shows regular exercise preserves ovarian reserve through adiponectin-mTOR signaling, offering a new target for extending women's reproductive and overall healthspan.
South Korean biotech Rznomics redesigned its circular RNA platform, achieving sevenfold efficiency gains and unlocking larger therapeutic genes.
Mabwell's ST2-blocking antibody 9MW1911 cut severe COPD exacerbations by up to 100% at the highest dose, offering hope for aging lungs.
