Plaque as Cumulative Exposure: apoB, Lp(a), Imaging and Inherited Risk in the Patient Whose Cholesterol Looks Fine

A clinical framework for atherosclerosis as lifetime particle exposure rather than a ten-year risk percentage — how to combine apoB, Lp(a), coronary imaging and inherited risk into a decision about when to start treating, and how to explain a 'normal' lipid panel that isn't reassuring.